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Article

Experimental characterization of the denatured state ensemble of proteins.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009

Cho Jae-Hyun, Raleigh Daniel P

Abstract excerpt

The traditional view of the denatured state ensemble of proteins is that it behaves as a classic random coil. This model has important implications for the analysis of protein stability, protein folding, and cooperativity; namely that the effects of mutations on the free energy of the denatured state ensemble can be ignored. This assumption, which is still routinely made, at least at the implicit level, greatly...

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PMID: 19157090
DOI: 10.1007/978-1-59745-367-7_14

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DSE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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