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Article

The Shh signalling pathway in early tooth development.

Cellular and molecular biology (Noisy-le-Grand, France) - 1 Jul 1999

Hardcastle Z, Hui C C, Sharpe P T

Abstract excerpt

The Sonic Hedgehog (Shh) signalling pathway has been proposed to play an important role in mammalian tooth development. We describe the spatial and temporal expression of genes in this pathway during early tooth development and interpret these patterns in terms of the likely roles of Shh signalling. We show that the two putative receptors of the Shh ligand, Ptc and Ptch-2, localise in different cells, suggesting...

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PMID: 10512189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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