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Article

Multidrug resistance and the lung resistance-related protein in human colon carcinoma SW-620 cells.

Journal of the National Cancer Institute - 6 Oct 1999

Kitazono M, Sumizawa T, Takebayashi Y, Chen Z S, Furukawa T, Nagayama S, Tani A, Takao S, Aikou T, Akiyama S

Abstract excerpt

BACKGROUND: Lung resistance-related protein (LRP), the major vault protein in humans, is sometimes overexpressed in multidrug-resistant cells. Because cells transfected with the LRP gene did not express the multidrug-resistant phenotype, we investigated whether LRP is involved in multidrug resistance. METHODS: SW-620 cells, a human colon carcinoma cell line, alone or transfected with an expression vector carrying...

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Identifiers

PMID: 10511592
DOI: 10.1093/jnci/91.19.1647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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