Article
A random model approach to mapping quantitative trait loci for complex binary traits in outbred populations.
Genetics - 1 Oct 1999
Yi N, Xu S
Abstract excerpt
Mapping quantitative trait loci (QTL) for complex binary traits is more challenging than for normally distributed traits due to the nonlinear relationship between the observed phenotype and unobservable genetic effects, especially when the mapping population contains multiple outbred families. Because the number of alleles of a QTL depends on the number of founders in an outbred population, it is more appropriate...
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