Article
Using the mixed model for interval mapping of quantitative trait loci in outbred line crosses.
Genetical research - 1 Apr 2001
Nagamine Y, Haley C S
Abstract excerpt
Interval mapping by simple regression is a powerful method for the detection of quantitative trait loci (QTLs) in line crosses such as F2 populations. Due to the ease of computation of the regression approach, relatively complex models with multiple fixed effects, interactions between QTLs or between QTLs and fixed effects can easily be accommodated. However, polygenic effects, which are not targeted in QTL...
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