Article
Bayesian mapping of quantitative trait loci for complex binary traits.
Genetics - 1 Jul 2000
Yi N, Xu S
Abstract excerpt
A complex binary trait is a character that has a dichotomous expression but with a polygenic genetic background. Mapping quantitative trait loci (QTL) for such traits is difficult because of the discrete nature and the reduced variation in the phenotypic distribution. Bayesian statistics are proved to be a powerful tool for solving complicated genetic problems, such as multiple QTL with nonadditive effects, and...
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