Iteratively reweighted least squares mapping of quantitative trait loci.

doi:10.1023/a:1021617618150

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Article

Iteratively reweighted least squares mapping of quantitative trait loci.

Behavior genetics - 1 Sept 1998

Xu S

Abstract excerpt

Mapping quantitative trait loci (QTL) is a typical problem of regression with uncertain independent variables because the genotype of a putative QTL is not observed. Rather, the genotype is inferred from marker information. The method of maximum likelihood (ML) methods is considered to be the opt...

Topics

Chromosome Mapping
Genetic Linkage
Genetic Markers
Genotype
Humans
Least-Squares Analysis
Likelihood Functions
Models, Genetic
Monte Carlo Method
Quantitative Trait, Heritable
Regression Analysis

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