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Article

Effect of pH on hen egg white lysozyme production and evolution of a recombinant strain of Aspergillus niger.

Journal of biotechnology - 24 Sept 1999

Mainwaring D O, Wiebe M G, Robson G D, Goldrick M, Jeenes D J, Archer D B, Trinci A P

Abstract excerpt

An Aspergillus niger strain (B1) transformed to produce mature hen egg white lysozyme (HEWL) from a glucoamylase fusion protein under control of the A. niger glucoamylase promoter was grown in glucose-limited chemostat culture at a dilution rate of 0.07 h-1 at various pH values. Maximum HEWL production (9.3 mg g-1; specific production rate = 0.65 mg g-1 per h) was obtained at pH 4.5. However, in chemostat...

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PMID: 10510855
DOI: 10.1016/s0168-1656(99)00123-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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