Article
The effect of pH on glucoamylase production, glycosylation and chemostat evolution of Aspergillus niger.
Biochimica et biophysica acta - 15 Aug 2001
Wallis G L, Swift R J, Atterbury R, Trappe S, Rinas U, Hemming F W, Wiebe M G, Trinci A P, Peberdy J F
Abstract excerpt
The effect of ambient pH on production and glycosylation of glucoamylase (GAM) and on the generation of a morphological mutant produced by Aspergillus niger strain B1 (a transformant containing an additional 20 copies of the homologous GAM glaA gene) was studied. We have shown that a change in the pH from 4 to 5.4 during continuous cultivation of the A. niger B1 strain instigates or accelerates the spontaneous...
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