Article
Identification of a novel actin binding motif in smooth muscle myosin light chain kinase.
The Journal of biological chemistry - 8 Oct 1999
Smith L, Su X, Lin P, Zhi G, Stull J T
Abstract excerpt
Phosphorylation of the 20-kDa regulatory light chain of myosin catalyzed by a Ca(2+)/calmodulin-dependent myosin light chain kinase is important in the initiation of smooth muscle contraction and other contractile processes in non-muscle cells. It has been previously shown that residues 1-142 of smooth muscle myosin light chain kinase are necessary for high-affinity binding to actin-containing filaments in cells...
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