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Article

Genetic and environmental conditions that increase longevity in Caenorhabditis elegans decrease metabolic rate.

Proceedings of the National Academy of Sciences of the United States of America - 28 Sept 1999

Van Voorhies W A, Ward S

Abstract excerpt

Mutations that increase the longevity of the soil nematode Caenorhabditis elegans could define genes involved in a process specific for aging. Alternatively, these mutations could reduce animal metabolic rate and increase longevity as a consequence. In ectotherms, longevity is often negatively correlated with metabolic rate. Consistent with these observations, environmental conditions that reduce the metabolic...

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PMID: 10500188
DOI: 10.1073/pnas.96.20.11399
PMCID: PMC18045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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