Article
Heterotopic endochondrial ossification with mixed tumor formation in C3(1)/Tag transgenic mice is associated with elevated TGF-beta1 and BMP-2 expression.
Oncogene - 23 Sept 1999
Maroulakou I G, Shibata M A, Anver M, Jorcyk C L, Liu M l, Roche N, Roberts A B, Tsarfaty I, Reseau J, Ward J, Green J E
Abstract excerpt
Transgenic mice which express the simian virus 40 large T-antigen (Tag) under the regulatory control of the hormone responsive rat C3(1) gene develop unusual lesions of heterotopic bone growth associated with mixed tumor formation arising from eccrine sweat glands found only in the foot pads of mice, ischiocavernosus muscle adjacent to bulbourethral glands and occasionally the salivary and mammary glands. These...
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