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Article

Use of tissue recombination to predict phenotypes of transgenic mouse models of prostate carcinoma.

Laboratory investigation; a journal of technical methods and pathology - 1 Sept 2005

Ishii Kenichiro, Shappell Scott B, Matusik Robert J, Hayward Simon W

Abstract excerpt

Transgenic mouse models of cancer represent a powerful approach for exploring disease processes and testing potential therapeutic interventions. Currently, it is difficult to predict if a specific genetic manipulation will result in a desirable phenotype. The present study tests the idea that tissue recombinants recapitulate the pathologic features of the neoplastic prostate seen in transgenic mice, and would...

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PMID: 15980886
DOI: 10.1038/labinvest.3700310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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