Article
Combination of polymorphisms in OB-R and the OB gene associated with insulin resistance in Nauruan males.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Aug 1999
de Silva A M, Walder K R, Aitman T J, Gotoda T, Goldstone A P, Hodge A M, de Courten M P, Zimmet P Z, Collier G R
Abstract excerpt
OBJECTIVE: To investigate the relationship between polymorphisms in the OB-R and OB genes and metabolic markers for obesity and glucose intolerance in a population of Nauruan men. In addition, we examined the effect of the simultaneous presence of the three polymorphisms on the phenotype of individuals in this population. DESIGN AND SUBJECTS: This study was conducted in a population from the Pacific Island of...
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