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Article

Genetic polymorphisms associated with overweight and obesity in uncontrolled Type 2 diabetes mellitus.

Biomarkers in medicine - 1 Jan 2016

Kasim Nor Bahirah, Huri Hasniza Zaman, Vethakkan Shireene Ratna, Ibrahim Luqman, Abdullah Bashar Mudhaffar

Abstract excerpt

Generally, obese and overweight individuals display higher free fatty acid levels, which stimulate insulin resistance. The combination of overweight or obesity with insulin resistance can trigger Type 2 diabetes mellitus (T2DM) and are primary contributing factors to the development of uncontrolled T2DM. Genetic polymorphisms also play an important role as they can impact a population's susceptibility to becoming...

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to Adiponectin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Insulin Receptor Substrate Proteins

Share to Obesity

Share to Overweight

Share to PPAR gamma

Share to Receptors, Leptin

Source

Identifiers

PMID: 26999420
DOI: 10.2217/bmm-2015-0037

Genes

ADIPOQ
GRB14
IRS2
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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