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Article

Reverse Genetics in Zebrafish: Mutants, Morphants, and Moving Forward.

Trends in cell biology - 1 Feb 2016

Lawson Nathan D

Abstract excerpt

Gene editing in zebrafish has begun to reveal discordance between mutant phenotypes and those associated with knockdown via morpholino oligonucleotides (MOs). These studies suggest that MOs should not be used as a standalone tool and underscore the need for guidelines that require defined mutants to assess gene function in zebrafish.

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Identifiers

PMID: 26739910
DOI: 10.1016/j.tcb.2015.11.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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