Article
Mutations in the amino terminus of foamy virus Gag disrupt morphology and infectivity but do not target assembly.
Journal of virology - 1 Jul 2008
Life Rachel B, Lee Eun-Gyung, Eastman Scott W, Linial Maxine L
Abstract excerpt
Foamy viruses (FVs) assemble using pathways distinct from those of orthoretroviruses. FV capsid assembly takes place near the host microtubule-organizing center (MTOC). Assembled capsids then migrate by an unknown mechanism to the trans-Golgi network to colocalize with the FV glycoprotein, Env. Interaction with Env is required for FV capsid egress from cells; the amino terminus of FV Gag contains a cytoplasmic...
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