A tyrosine motif in the cytoplasmic domain of mason-pfizer monkey virus is essential for the incorporation of glycoprotein into virions.

doi:10.1128/jvi.77.9.5192-5200.2003

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Article

A tyrosine motif in the cytoplasmic domain of mason-pfizer monkey virus is essential for the incorporation of glycoprotein into virions.

Journal of virology - 1 May 2003

Song Chisu, Dubay Susan R, Hunter Eric

Abstract excerpt

Mason-Pfizer monkey virus (M-PMV) encodes a transmembrane (TM) glycoprotein with a 38-amino-acid-long cytoplasmic domain. After the release of the immature virus, a viral protease-mediated cleavage occurs within the cytoplasmic domain, resulting in the loss of 17 amino acids from the carboxy terminus. This maturational cleavage occurs between a histidine at position 21 and a tyrosine at position 22 in the...

Topics

Amino Acid Motifs
Amino Acid Sequence
Animals
COS Cells
Cell Fusion
Cytoplasm
Endocytosis
Gene Expression Regulation, Viral
Genes, env
Glycoproteins
Mason-Pfizer monkey virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Membrane Fusion

Molecular Sequence Data

Mutation

Tyrosine

Viral Envelope Proteins

Virion

Source

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Identifiers

PMID: 12692221
DOI: 10.1128/jvi.77.9.5192-5200.2003
PMCID: PMC153939

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