Article
Transmission of a minor variant of transcriptionally active HIV-1.
Scandinavian journal of infectious diseases - 1 Jan 1999
Machuca R, Schønning K, Hansen J E, Bruun L, Fomsgaard A, Nielsen C
Abstract excerpt
We investigated the genotypic variation of pro-viral human immunodeficiency virus type 1 (HIV-1) DNA in a virus donor-recipient pair by comparing sequences from the HIV-1 V3 region of the gp120 gene and the p17gag gene. We found that the transmitted virus was a minor variant in the donor's virus population in blood. Possible selection mechanisms within the host (neutralization by antibodies) were studied in order...
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