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Article

Selection, recombination, and G----A hypermutation of human immunodeficiency virus type 1 genomes.

Journal of virology - 1 Apr 1991

Vartanian J P, Meyerhans A, Asjö B, Wain-Hobson S

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) isolates are genetically so heterogeneous that they must be described in terms of populations of related but distinct genomes called quasispecies. A recent study of the influence of ex vivo culturing on HIV-1 quasispecies demonstrated that usually low-abundance genomes outgrew the more prominent forms. Here it is shown that multiple passages of an HIV-1 isolate on...

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Identifiers

PMID: 2002543
DOI: 10.1128/JVI.65.4.1779-1788.1991
PMCID: PMC239985

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