Article
Host genomic HIV restriction factors modulate the response to dendritic cell-based treatment against HIV-1.
Human vaccines & immunotherapeutics - 1 Jan 2014
Pontillo Alessandra, Da Silva Ronaldo C, Moura Ronald, Crovella Sergio
Abstract excerpt
Host genome is still poorly investigated in the context of vaccine or immunotherapy, however recently findings emphasized that it may affect the response to those treatments. In our retrospective study we evaluated the effect of HIV-1 genetic restriction factors on the response to dendritic cell (DC)-based immunotherapy in a Brazilian cohort of HIV positive (HIV+) patients that underwent a phase I clinical trial...
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