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Article

Essential requirement for Pax6 in control of enteroendocrine proglucagon gene transcription.

Molecular endocrinology (Baltimore, Md.) - 1 Sept 1999

Hill M E, Asa S L, Drucker D J

Abstract excerpt

The primary function of islet A cells is the synthesis and secretion of glucagon, an essential hormonal regulator of glucose homeostasis. The proglucagon gene is also expressed in enteroendocrine L cells of the intestinal epithelium, which produce glucagon-like peptide 1 (GLP-1) and glucagon-like peptide 2 (GLP-2), regulators of insulin secretion and intestinal growth, respectively. We show here that Pax6, a...

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Source

Identifiers

PMID: 10478839
DOI: 10.1210/mend.13.9.0340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Essential requirement for Pax6 in control of enteroendocrine proglucagon gene transcription.PMID 10478839Read ↗

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