Article
Association of beta2-adrenergic receptor polymorphisms with severe asthma.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Aug 2000
Holloway J W, Dunbar P R, Riley G A, Sawyer G M, Fitzharris P F, Pearce N, Le Gros G S, Beasley R
Abstract excerpt
BACKGROUND: There is considerable interest in the role of different candidate loci in the development of asthma. This study investigates the association between asthma severity and previously identified polymorphisms at two sites within the beta2-adrenergic receptor (beta2AR) gene: the Arg16-->Gly16 and Gln27-->Glu27 alleles. METHODS: Restriction enzyme analysis of amplified beta2AR gene products (PCR-RFLP) was...
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