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Article

Molecular detection of tumour DNA in serum and peritoneal fluid from ovarian cancer patients.

British journal of cancer - 1 Aug 1999

Hickey K P, Boyle K P, Jepps H M, Andrew A C, Buxton E J, Burns P A

Abstract excerpt

We have analysed DNA extracted from the serum and peritoneal fluid of 20 ovarian cancer patients for the presence of tumour-specific genetic alterations. The 20 patients included six with stage Ia disease. Using six polymorphic microsatellite loci we were able to detect novel alleles or loss of heterozygosity in 17/20 serum samples and 12/19 peritoneal fluid samples. Tumour-specific abnormalities were detected in...

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Identifiers

PMID: 10468300
DOI: 10.1038/sj.bjc.6690601
PMCID: PMC2363116

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Source receipt: pubmed, retrieved 7 Sept 2026.

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