Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential requirements of the fused kinase for hedgehog signalling in the Drosophila embryo.

Development (Cambridge, England) - 1 Sept 1999

Thérond P P, Limbourg Bouchon B, Gallet A, Dussilol F, Pietri T, van den Heuvel M, Tricoire H

Abstract excerpt

The two signalling proteins, Wingless and Hedgehog, play fundamental roles in patterning cells within each metamere of the Drosophila embryo. Within the ventral ectoderm, Hedgehog signals both to the anterior and posterior directions: anterior flanking cells express the wingless and patched Hedgehog target genes whereas posterior flanking cells express only patched. Furthermore, Hedgehog acts as a morphogen to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryonic Induction
Share to Gastrula

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hedgehog Proteins

Share to Insect Proteins

Share to Protein Processing, Post-Translational

Share to Receptors, G-Protein-Coupled

Share to Smoothened Receptor

Share to Wnt1 Protein

Source

Identifiers

PMID: 10457013
DOI: 10.1242/dev.126.18.4039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential requirements of the fused kinase for hedgehog signalling in the Drosophila embryo.PMID 10457013Read ↗

Distinct pathways for autocrine and paracrine Wingless signalling in Drosophila embryos.Semantic proximity Read ↗

A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing.Semantic proximity Read ↗

Modulation of the Suppressor of fused protein regulates the Hedgehog signaling pathway in Drosophila embryo and imaginal discs.Semantic proximity Read ↗

Notch and Wingless modulate the response of cells to Hedgehog signalling in the Drosophila wing.Semantic proximity Read ↗

A role for wingless in the segmental gradient of Drosophila?Semantic proximity Read ↗

The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation.Semantic proximity Read ↗

groucho and hedgehog regulate engrailed expression in the anterior compartment of the Drosophila wing.Semantic proximity Read ↗

Fused-dependent Hedgehog signal transduction is required for somatic cell differentiation during Drosophila egg chamber formation.Semantic proximity Read ↗

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway.Semantic proximity Read ↗

Induction of a mirror-image duplication of anterior wing structures by localized hedgehog expression in the anterior compartment of Drosophila melanogaster wing imaginal discs.Semantic proximity Read ↗

Interactions between fused, a segment-polarity gene in Drosophila, and other segmentation genes.Semantic proximity Read ↗

In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.