Article
A role for wingless in the segmental gradient of Drosophila?
Development (Cambridge, England) - 1 Feb 1993
Sampedro J, Johnston P, Lawrence P A
Abstract excerpt
The wild-type functions of the Wnt family of genes are still little understood (for review see Nusse and Varmus, Cell 69, 1073-1087, 1992). In Drosophila, the wingless (D-Wnt-1) protein is expressed in segmental stripes: its absence leads to a complete failure of segmentation, loss of engrailed expression and lack of pattern in the cuticle. A predominating hypothesis is that the spatial distribution of wingless...
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