Article
Gene organisation, sequence variation and isochore structure at the centromeric boundary of the human MHC.
Journal of molecular biology - 27 Aug 1999
Stephens R, Horton R, Humphray S, Rowen L, Trowsdale J, Beck S
Abstract excerpt
We have mapped and sequenced the region immediately centromeric of the human major histocompatibility complex (MHC). A cluster of 13 genes/pseudogenes was identified in a 175 kb PAC linking the TAPASIN locus with the class II region. It includes two novel human genes (BING4 and SACM2L) and a thus far unnoticed human leucocyte antigen (HLA) class II pseudogene, termed HLA-DPA3. Analysis of the G+C content revealed...
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