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Article

Mannose-binding lectin deficiency associated with neutrophil chemotactic unresponsiveness to C5a.

The Journal of allergy and clinical immunology - 1 Aug 1999

Ten R M, Carmona E M, Babovic-Vuksanovic D, Katzmann J A

Abstract excerpt

BACKGROUND: Mannose-binding lectin (MBL) plays an important role in host defense by activating the complement cascade. OBJECTIVE: Three children with a history of recurrent infections since infancy were found to have MBL deficiency associated with a neutrophil chemotactic unresponsiveness specific to C5a. We have studied the genomic sequence of the C5a receptor (C5aR) in 2 of the subjects to determine whether...

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Identifiers

PMID: 10452765
DOI: 10.1016/s0091-6749(99)70387-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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