Article
Evidence of an association between mannose binding lectin codon 54 polymorphism and adenoidectomy and/or tonsillectomy in children.
International journal of pediatric otorhinolaryngology - 1 Aug 2007
Koturoglu Guldane, Onay Huseyin, Midilli Rasit, Pehlivan Sacide, Eren Erdem, Itirli Gulcin, Kurugol Zafer, Apaydin Fazil, Ozkinay Cihangir, Ozkinay Ferda
Abstract excerpt
Mannose binding lectin (MBL) is a calcium-dependent lectin that plays an important role innate immunity by activating the complement pathway. There have been a number of studies describing an association between the MBL genotype and disease susceptibility. MBL deficiency has been described as one of the factors leading to a number of infections in children with recurrent upper respiratory tractus infections...
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