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Article

C4A deficiency in children and adolescents with recurrent respiratory infections.

Human immunology - 1 May 2012

Kainulainen Leena, Peltola Ville, Seppänen Mikko, Viander Markku, He Qiushui, Lokki Marja-Liisa, Ruuskanen Olli

Abstract excerpt

Increased susceptibility to recurrent viral and bacterial respiratory infections in children and young adults is not well understood. To evaluate the role of complement factor C4 in the defense against respiratory infections, we studied complement factor C4 allotypes C4A and C4B and copy numbers of C4A and C4B genes in 84 children and young adults with recurrent acute otitis media, sinusitis, or pneumonia and in...

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Identifiers

PMID: 22406254
DOI: 10.1016/j.humimm.2012.02.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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