Article
HIV-1 subtype C syncytium- and non-syncytium-inducing phenotypes and coreceptor usage among Ethiopian patients with AIDS.
AIDS (London, England) - 30 Jul 1999
Abebe A, Demissie D, Goudsmit J, Brouwer M, Kuiken C L, Pollakis G, Schuitemaker H, Fontanet A L, Rinke de Wit T F
Abstract excerpt
OBJECTIVE: To assess syncytium-inducing (SI) and non-syncytium-inducing (NSI) frequencies, coreceptor usage and gp120 V3 sequences of HIV-1 isolates from Ethiopian AIDS patients. PATIENTS: Cross-sectional study on 48 hospitalized AIDS patients (CD4 T cells < 200 x 10(6) cell/l) with stage III or IV of the WHO staging system for HIV-1 infection and disease. METHODS: Peripheral blood mononuclear cells (PBMC) from...
Topics
- Adult
- Cross-Sectional Studies
- DNA, Viral
- Ethiopia
- Female
- Giant Cells
- HIV Envelope Protein gp120
- HIV Infections
- HIV-1
- Humans
- Immunophenotyping
- Leukocytes, Mononuclear
- Male
- Peptide Fragments