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Article

Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype.

Journal of virology - 1 Oct 1997

Björndal A, Deng H, Jansson M, Fiore J R, Colognesi C, Karlsson A, Albert J, Scarlatti G, Littman D R, Fenyö E M

Abstract excerpt

The biological phenotype of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to the severity of the HIV infection. Here we show that the two previously described groups of rapid/high, syncytium-inducing (SI) and slow/low, non-syncytium-inducing (NSI) isolates are distinguished by their ability to utilize different chemokine receptors for entry into target cells. Recent studies have...

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Source

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Identifiers

PMID: 9311827
DOI: 10.1128/JVI.71.10.7478-7487.1997
PMCID: PMC192094

Genes

CCR5
CXCR4
CCR3
CCR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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