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Article

Expression of insulin-like growth factor-1 receptor in synovial sarcoma: association with an aggressive phenotype.

Cancer research - 1 Aug 1999

Xie Y, Skytting B, Nilsson G, Brodin B, Larsson O

Abstract excerpt

It is well known that insulin-like growth factor-1 receptor (IGF-1R) plays a crucial role in proliferation and survival of transformed cells. Overexpression of IGF-1R in certain tumors has been reported, but there is still little known about its importance in vivo. Here, we evaluated the IGF-1R levels in 35 human synovial sarcoma tumors by Western blot and reverse transcriptase-PCR. In 18 of these, IGF-1R was...

Read the complete abstract on PubMed

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Share to Bone Neoplasms
Share to Insulin-Like Growth Factor I
Share to Neoplasm Invasiveness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Proteins

Share to Oncogene Proteins, Fusion

Share to Receptor, IGF Type 1

Share to RNA, Neoplasm

Share to Sarcoma, Ewing

Source

Identifiers

PMID: 10446966

Genes

SSX1
SSX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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