Article
Mouse models of spike-wave epilepsy.
Epilepsia - 1 Jan 1999
Barclay J, Rees M
Abstract excerpt
The mouse is a well-established model for human genetic disorders. An increasing number of single-gene human diseases are being elucidated through the use of mouse models. Recently genes for three of the six well-characterised single locus models for human spike-wave epilepsy have been isolated and published. The tottering mouse has been shown to be due to mutations in the gene encoding the high voltage-activated...
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