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Article

Plasma factor VII-activating protease is increased by oral contraceptives and induces factor VII activation in-vivo.

Thrombosis research - 1 Nov 2011

Sidelmann Johannes J, Skouby Sven O, Kluft Cornelis, Winkler Ulrich, Vitzthum Frank, Schwarz Herbert, Gram Jørgen, Jespersen Jørgen

Abstract excerpt

UNLABELLED: Oral contraceptive (OC) use influences the hemostatic system significantly and is a risk factor for development of cardiovascular disease. Factor VII-activating protease (FSAP) has potential effects on hemostasis. The 1601GA genotype of the 1601G/A polymorphism in the FSAP gene expresses a FSAP alloenzyme with reduced pro-fibrinolytic activity. Presently, we address whether OC use and OC formulation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21737124
DOI: 10.1016/j.thromres.2011.06.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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