Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Progressive decline in insulin levels in Rabson-Mendenhall syndrome.

The Journal of clinical endocrinology and metabolism - 1 Aug 1999

Longo N, Wang Y, Pasquali M

Abstract excerpt

Mutations in the insulin receptor gene cause the severe insulin-resistant syndromes leprechaunism and Rabson-Mendenhall syndrome, whose metabolic features include fasting hypoglycemia, post-prandial hyperglycemia, and extremely elevated insulin levels. Patients with Rabson-Mendenhall syndrome have a protracted course and eventually develop ketoacidosis. To determine the mechanism causing this progression and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Insulin
Share to Insulin-Like Growth Factor I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin Receptor Substrate Proteins

Share to Insulin Resistance

Share to Phosphoproteins

Share to Receptor, Insulin

Share to Syndrome

Source

Identifiers

PMID: 10443650
DOI: 10.1210/jcem.84.8.5902

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Progressive decline in insulin levels in Rabson-Mendenhall syndrome.PMID 10443650Read ↗

Management challenges of Rabson Mendenhall syndrome in a resource limited country: a case report.Semantic proximity Read ↗

Genotype-phenotype correlation in inherited severe insulin resistance.Semantic proximity Read ↗

Clinical course of genetic diseases of the insulin receptor (type A and Rabson-Mendenhall syndromes): a 30-year prospective.Semantic proximity Read ↗

Abnormal insulinemia.Semantic proximity Read ↗

Mechanisms of hormone resistance: lessons from insulin-resistant patients.Semantic proximity Read ↗

A syndrome of insulin resistance resembling leprechaunism in five sibs of consanguineous parents.Semantic proximity Read ↗

Lilly Lecture: molecular mechanisms of insulin resistance. Lessons from patients with mutations in the insulin-receptor gene.Semantic proximity Read ↗

Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study.Semantic proximity Read ↗

Leprechaunism (Donohue syndrome): a case bearing novel compound heterozygous mutations in the insulin receptor gene.Semantic proximity Read ↗

Insulin resistance: a chicken that has come to roost.Semantic proximity Read ↗

Metreleptin Improves Blood Glucose in Patients With Insulin Receptor MutationsSemantic proximity Read ↗

Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.