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Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study.

Diabetes - 1 Nov 2010

Keenan Hillary A, Sun Jennifer K, Levine Jared, Doria Alessandro, Aiello Lloyd P, Eisenbarth George, Bonner-Weir Susan, King George L

Abstract excerpt

OBJECTIVE: To evaluate the extent of pancreatic β-cell function in a large number of insulin-dependent diabetic patients with a disease duration of 50 years or longer (Medalists). RESEARCH DESIGN AND METHODS: Characterization of clinical and biochemical parameters and β-cell function of 411 Medalists with correlation with postmortem morphologic findings of 9 Medalists. RESULTS: The Medalist cohort, with a mean ±...

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Identifiers

PMID: 20699420
DOI: 10.2337/db10-0676
PMCID: PMC2963543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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