Article
Molecular genetic basis of pancreatic adenocarcinoma.
Genes, chromosomes & cancer - 1 Sept 1999
Hilgers W, Kern S E
Abstract excerpt
Pancreatic ductal adenocarcinoma is a complex genetic disease. As might be expected for a malignancy that is rather homogeneous in clinical presentation and behavior, a distinct subset of genes are found to be genetically inactivated in a majority of the tumors. A yet larger subset of genes experiences genetic inactivation at much lower frequencies. The latter subset could solely reflect a somewhat trivial...
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