Article
Pancreatic cancer biology and genetics.
Nature reviews. Cancer - 1 Dec 2002
Bardeesy Nabeel, DePinho Ronald A
Abstract excerpt
Pancreatic ductal adenocarcinoma is an aggressive and devastating disease, which is characterized by invasiveness, rapid progression and profound resistance to treatment. Advances in pathological classification and cancer genetics have improved our descriptive understanding of this disease; however, important aspects of pancreatic cancer biology remain poorly understood. What is the pathogenic role of specific...
Topics
- Adenocarcinoma
- Animals
- Cell Differentiation
- Genetic Predisposition to Disease
- Humans
- Mice
- Mice, Knockout
- Neoplasm Metastasis
- Pancreas
- Pancreatic Neoplasms