Article
Identification of a new regulator in Streptococcus pneumoniae linking quorum sensing to competence for genetic transformation.
Journal of bacteriology - 1 Aug 1999
Lee M S, Morrison D A
Abstract excerpt
Competence for genetic transformation in Streptococcus pneumoniae is regulated by a quorum-sensing system encoded by two genetic loci, comCDE and comAB. Additional competence-specific operons, cilA, cilB, cilC, cilD, cilE, cinA-recA, coiA, and cfl, involved in the DNA uptake process and recombination, share an unusual consensus sequence at -10 and -25 in the promoter, which is absent from the promoters of comAB...
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