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Article

Direct involvement of DprA, the transformation-dedicated RecA loader, in the shut-off of pneumococcal competence.

Proceedings of the National Academy of Sciences of the United States of America - 12 Mar 2013

Mirouze Nicolas, Bergé Mathieu A, Soulet Anne-Lise, Mortier-Barrière Isabelle, Quentin Yves, Fichant Gwennaele, Granadel Chantal, Noirot-Gros Marie-Françoise, Noirot Philippe, Polard Patrice, Martin Bernard, Claverys Jean-Pierre

Abstract excerpt

Natural bacterial transformation is a genetically programmed process allowing genotype alterations that involves the internalization of DNA and its chromosomal integration catalyzed by the universal recombinase RecA, assisted by its transformation-dedicated loader, DNA processing protein A (DprA). In Streptococcus pneumoniae, the ability to internalize DNA, known as competence, is transient, developing suddenly...

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Share to Bacterial Proteins
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Membrane Proteins

Share to Protein Structure, Tertiary

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Identifiers

PMID: 23440217
DOI: 10.1073/pnas.1219868110
PMCID: PMC3600483

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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