Article
Genetic analysis of HLA- and HPA-typing in idiopathic (autoimmune) thrombocytopenic purpura patients treated with cepharanthin.
Autoimmunity - 1 Jan 1999
Nomura S, Matsuzaki T, Yamaoka M, Ozaki Y, Nagahama M, Yoshimura C, Kagawa H, Nakayama S, Fukuhara S
Abstract excerpt
We performed genetic analysis of human leukocyte antigen (HLA) and human platelet antigen (HPA) in 45 patients with cepharanthin-treated idiopathic thrombocytopenic purpura. HLA-typing was performed by the polymerase chain reaction-restriction fragment length polymorphism method, and HPA-typing by a polymerase chain reaction-sequence-specific primer method. There were 14 responders and 31 nonresponders....
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