Article
Primary pulmonary hypertension, tissue plasminogen activator antibodies, and HLA-DQ7.
American journal of respiratory and critical care medicine - 1 Jan 1997
Morse J H, Barst R J, Fotino M, Zhang Y, Flaster E, Gharavi A E, Fritzler M J, Dominguez M, Angles-Cano E
Abstract excerpt
Antibodies to fibrin-bound tissue plasminogen activator (tPA) have been found in autoimmune diseases with vascular injury, such as systemic lupus erythematosus and scleroderma. The purpose of this study was to determine whether patients with primary pulmonary hypertension (PPH) have an immunogenetically determined response to fibrin-bound tPA. Antibodies to fibrin-bound tPA were determined in three patient...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.