Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of human leukocyte antigens as predisposing and/or protective factors in patients with idiopathic thrombotic thrombocytopenic purpura.

Annals of hematology - 1 Apr 2012

John Marie-Luise, Hitzler Walter, Scharrer Inge

Abstract excerpt

Fifty-four adult German patients suffering from idiopathic thrombotic thrombocytopenic purpura (TTP) have been examined for HLA class II. All patients presented autoantibodies against ADAMTS13 and ADAMTS13 activity levels <5%. Blood samples have been analyzed for HLA-DRB1 and DQB1 alleles using sequence-specific primer PCR and sequence-specific oligonucleotide PCR. Reference data of German bone marrow and blood...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADAM Proteins
Share to ADAMTS13 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Susceptibility

Share to Germany

Share to Histocompatibility Antigens Class II

Share to HLA-DQ Antigens

Share to HLA-DRB1 Chains

Share to Purpura, Thrombotic Thrombocytopenic

Source

Identifiers

PMID: 22203269
DOI: 10.1007/s00277-011-1384-z

Genes

ADAMTS13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of human leukocyte antigens as predisposing and/or protective factors in patients with idiopathic thrombotic thrombocytopenic purpura.PMID 22203269Read ↗

Human leukocyte antigen association in idiopathic thrombotic thrombocytopenic purpura: evidence for an immunogenetic link.Semantic proximity Read ↗

Identification of HLA alleles involved in immune thrombotic thrombocytopenic purpura patients from Turkey.Semantic proximity Read ↗

The role of human leukocyte antigen DRB1-DQB1 haplotypes in the susceptibility to acquired idiopathic thrombotic thrombocytopenic purpura.Semantic proximity Read ↗

Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers.Semantic proximity Read ↗

Familial acquired thrombotic thrombocytopenic purpura: immunogenetic link with HLA-DRB1*11 and DQB1*03 antigens.Semantic proximity Read ↗

Emerging Concepts in Immune Thrombotic Thrombocytopenic Purpura.Semantic proximity Read ↗

[Immune-mediated thrombotic thrombocytopenic purpura and susceptible HLA alleles].Semantic proximity Read ↗

[Study on the relations between HLA-DRB1 alleles and idiopathic thrombocytopenic purpura in children].Semantic proximity Read ↗

The relation between HLA-DRB1 alleles and the outcome of therapy in children with idiopathic thrombocytopenic purpura.Semantic proximity Read ↗

High prevalence of infectious events in thrombotic thrombocytopenic purpura and genetic relationship with toll-like receptor 9 polymorphisms: experience of the French Thrombotic Microangiopathies Reference Center.Semantic proximity Read ↗

Human platelet antigen 1, 2 and 5 gene polymorphisms in Egyptians and their potential association with susceptibility to immune thrombocytopenic purpura in Egyptian patients.Semantic proximity Read ↗

Foetal and neonatal alloimmune thrombocytopenia - The role of the HLA-DRB3*01:01 allele for HPA-1a-immunisation and foetal/neonatal outcome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.