Article
Identification of HLA alleles involved in immune thrombotic thrombocytopenic purpura patients from Turkey.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Sept 2024
Kikili Cevat İlteriş, Kivanç Demet, Ortaboz Damla, Şentürk Çiftçi Hayriye, Özbalak Mustafa Murat, Yenerel Mustafa Nuri, Nalçaci Meliha, Ar Muhlis Cem, Oğuz Fatma Savran, Beşişik Sevgi Kalayoğlu
Abstract excerpt
Thrombotic thrombocytopenic purpura (TTP) is one of the rare group disorders classified as thrombotic microangiopathies (TMAs). Approximately 90% of TTP developed immune-mediation by the formation of antibodies against the enzyme ADAMTS-13. The exact cause is unknown. To establish an association between human leukocyte antigen (HLA) and autoimmune basis, as susceptibility or protection against the disease, we...
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