Article
Human platelet antigen genotyping using a fluorescent SSCP technique with an automatic sequencer.
British journal of haematology - 1 Nov 1998
Quintanar A, Jallu V, Legros Y, Kaplan C
Abstract excerpt
The typing of human platelet antigens (HPA) can be useful in many clinical situations such as neonatal alloimmune thrombocytopenia, post-transfusion purpura, and platelet transfusion refractoriness. The fluorescent-based single-strand conformation polymorphism (F-SSCP) technique is a fast and con...
Topics
- Adult
- Antigens, Human Platelet
- Blood Platelets
- DNA Mutational Analysis
- Female
- Genotype
- Humans
- Infant, Newborn
- Male
- Maternal-Fetal Exchange
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single-Stranded Conformational
- Pregnancy
- Thrombocytopenia