Article
A naturally occurring genetic variant in the human chorionic gonadotropin-beta gene 5 is assembly inefficient.
Endocrinology - 1 Aug 1999
Miller-Lindholm A K, Bedows E, Bartels C F, Ramey J, Maclin V, Ruddon R W
Abstract excerpt
The hCGbeta gene family is composed of six homologous genes linked in tandem repeat on chromosome 19; the order of the genes is 7, 8, 5, 1, 2, and 3. Previous studies have shown that hCGbeta gene 5 is highly expressed during the first trimester of pregnancy. The purpose of our study was to identify naturally occurring polymorphisms in hCGbeta gene 5 and determine whether these alterations affected hCG function....
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