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Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice.

Biology of reproduction - 1 Jul 2003

Matzuk Martin M, DeMayo Francesco J, Hadsell Lou Ann, Kumar T Rajendra

Abstract excerpt

Human CG is a pregnancy marker secreted by the placenta, and it utilizes the same receptors as does LH. Human CG is a heterodimer, and its subunits are expressed in tissues other than placenta. Similarly, LH/hCG receptors are also expressed in multiple tissues; however, the physiological significance of this expression is unknown. Free hCGbeta is efficiently secreted in vitro in transfected cells and is highly...

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PMID: 12672665
DOI: 10.1095/biolreprod.102.013953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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