Article
A vital role for glycosphingolipid synthesis during development and differentiation.
Proceedings of the National Academy of Sciences of the United States of America - 3 Aug 1999
Yamashita T, Wada R, Sasaki T, Deng C, Bierfreund U, Sandhoff K, Proia R L
Abstract excerpt
Glycosphingolipids (GSLs) are believed to be integral for the dynamics of many cell membrane events, including cellular interactions, signaling, and trafficking. We have investigated their roles in development and differentiation by eliminating the major synthesis pathway of GSLs through targeted...
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