Degradation of Candida albicans Can1 permease expressed in Saccharomyces cerevisiae.

Abstract excerpt

The Candida albicans amino-acid Can1 permease expressed in Saccharomyces cerevisiae is degraded in the vacuole after internalisation by endocytosis. The CaCan1 inactivation and degradation is slow and not inducible by ammonium ions or 'stress' conditions. Using Saccharomyces cerevisiae mutants defective in ubiquitin-protein ligase and ubiquitin-protein hydrolase we have shown that the degradation of heterologous...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amino Acid Transport Systems
• Share to Candida albicans
• Share to Endocytosis